SELECT 
  pfv.feature_id, 
  pfv.product_id, 
  pfv.variant_id, 
  fv.position, 
  fvd.variant 
FROM 
  cscart_product_features_values AS pfv 
  INNER JOIN cscart_product_feature_variants AS fv ON pfv.feature_id = fv.feature_id 
  AND pfv.variant_id = fv.variant_id 
  INNER JOIN cscart_product_feature_variant_descriptions AS fvd ON pfv.variant_id = fvd.variant_id 
  AND fvd.lang_code = 'en' 
WHERE 
  pfv.feature_id IN (548, 549) 
  AND pfv.product_id IN (278) 
  AND pfv.lang_code = 'en'

Query time 0.00063

Explain
id select_type table type possible_keys key key_len ref rows Extra
1 SIMPLE fv range PRIMARY,feature_id feature_id 3 7 Using index condition
1 SIMPLE pfv eq_ref PRIMARY,fl,variant_id,lang_code,product_id,fpl,idx_product_feature_variant_id PRIMARY 15 cscart_dev_4_16.fv.feature_id,const,cscart_dev_4_16.fv.variant_id,const 1 Using where; Using index
1 SIMPLE fvd eq_ref PRIMARY PRIMARY 9 cscart_dev_4_16.fv.variant_id,const 1 Using index condition

Result

feature_id product_id variant_id position variant
548 278 1195 3 Medium
549 278 1201 4 White